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Fifty-three (4.3%) patients in the cytisine group and 46 (3.7%) in the placebo group reported serious adverse events (SAEs) (94 events in the cytisine group and 90 events in the placebo group), which included 91 deaths (49 in the cytisine group and 42 in the placebo group)

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Palpitations could be caused by something as simple as stress, but they could also be signs of developing an irregular heart rhythm such as atrial fibrillation, which is a huge risk factor for having a stroke