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If you notice these early signs of lung damage from smoking, it's a critical signal to act

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Additionally, nicotine exposed mice show upregulated expression of VCAM-1, COX-2, platelet-derived growth factor (PDGF), and molecules involved in downstream of NF-B signaling pathway in aorta lesions [279]

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After we adjusted for the covariates, the diastolic blood pressure subtraction difference was greater in the hypertensive group than in the non-hypertensive group