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Description
Epigenetic and transcriptomic analyses have identified the amplification of the MYC family proto-oncogenes ( MYC , MYCL and MYCN ) [136], with MYCL being associated with the ASCL1-subtype and MYC being associated with other subtypes [126]
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UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation

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