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Classical culture systems with human small airway cells are unable to reproduce the breathing motions of the lung and commonly used laboratory animals cannot reflect human smoking because they breathe through their noses, and their inflammatory responses differ from those in humans

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Furthermore, 1 in 1000 children is seriously injured and 1 in 10 000 dies from related injuries.3 Children under 4 years of age are at the greatest risk of severe injury, and 79% of fatalities resulting from abuse occur in this age group (44% in children under 1 year of age).4 Despite the work being done by child protective services, there is still a clear tendency towards an increase in the prevalence of child abuse