effects of chewing tobacco during pregnancy Frontiers Publishing Partnerships How Tobacco Impacts Pregnancy
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The oxidation of (6R)-5,6,7,8-tetrahydro-L-biopterin, a cofactor of the eNOS [27, 31], leads to uncoupling of the eNOS enzymes regularly acting as dimers [26, 57]
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This forces the heart to work much harder to pump enough oxygenated blood to the body's tissues, contributing to high blood pressure, heart disease, and stamina issues
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