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The above discussed prazosin study suggests that suboptimal, either too low or too high, levels of noradrenergic transmission lead to negative mood states

This highlights the importance of using objective measures, such as biomarkers, in evaluating public health policies
Given the shorter latency for efficacy and the greater ease of use, it is generally advised to start with NRT rather than varenicline or bupropion, since the latter ones need an imbrication period while the patient is still smoking [4]

Captulo uno : Epidemia mundial de tabaquismo y papel de la reduccin del dao del tabaco
How Long Does It Take to Detox From nicotine addiction
