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This variation between studies may be due to the different puff routines used to generate the tobacco smoke (HCI vs ISO), aging of smoke particles over the puff routine (4 vs 8 mins) and dilution ratios in the smoke bags (75 vs 33)

Arterial blood gas: For people with significant respiratory distress, acute mental status changes, or shock, an arterial blood gas may be obtained

Discuss what they would say if a friend offers them a cigarette or an e-cigarette

Specifically, nasopharyngeal and laryngeal cancer should also merit careful observation in the future, as should stroke

One smoking expert said it appeared e-cigarettes were a "major contributor" to the trend