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Benzo[a]pyrene diol epoxide is the carcinogenic product of three enzymatic reactions: (1) Benzo[a]pyrene is first oxidized by cytochrome P4501A1 to form a variety of products, including (+)-benzo[a]pyrene 7,8-oxide

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3-EP levels were significantly higher when more smokers were present and when the tobacco smell was more intense

That being said, for heavy smokers and obese smokers, it may be a good idea to work on quitting smoking while also making other healthy lifestyle changes to control their weight. Other researchers are Jessica Yingst, research coordinator