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are there chemicals in pipe tobacco Compound Interest: The Cigarette Smoke & Their Effects Does Pipe Tobacco Have Additives?
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doi: 10.1002/14651858.CD003999.pub4 64 PeckhamEBrabynSCookLTewGGilbodyS
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Heterogeneity testing indicated limited variability (P = 0.067, I 2 = 45.2%)
Taken together, the findings implied that nicotine pouches and ECs might alter the oral microbiome and contribute to periodontal disease risk, though further quantitative studies are needed to confirm these preliminary results [69]
[1] Hydration levels: Increased hydration increases urine output, meaning the kidneys can eliminate nicotine faster
