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In this study we also adjusted for HHS, but compared to other SEP variables it was found to have little additional impact as a confounder of the active-smoking-mortality relationship

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Data availability Transcriptome sequencing data were deposited in the Genome Sequence Archive (GSA) at the National Genomics Data Center (accession number: CRA022734) ( Abbreviations TMV: Tobacco mosaic virus dpi: days post-inoculation SA: Salicylic acid JA: Jasmonic acid TOM: Tobamovirus multiplication protein PME: Pectin methylesterase SCMV: Sugarcane mosaic virus BCA: Bicinchoninic acid assay DEGs: Differentially expressed genes PCA: Principal component analysis GO: Gene Ontology KEGG: Kyoto Encyclopedia of Genes and Genomes DAMs: Differentially accumulated metabolites FC: Fold change VIP: Variable importance in the projection PLS-DA: Partial least squares discriminant analysis HCA: Hierarchical clustering analysis CP: Coat protein CHS: Chalcone synthase CHI: Chalcone isomerase LOX6: Lipoxygenase 6 JMT: Jasmonic acid O-methyltransferase SAR: Systemic acquired resistance References Ge Y, Liu K, Zhang J, Mu S, Hao X