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What this led to was a very aggressive grassroots tobacco-controlled movement that, over time, has really had a big impact, Brandt says

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The respiratory microbiome presents additional challenges due to its low microbial biomass, which makes it more susceptible to contamination during both sampling and sequencing
Similarly, a large prospective study from Italy found that among 592 smokers, 37 (3.7%) quit smoking within 5 years of diagnosis