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There are many studies comparing cigarettes with different tar yields as measured by smoking machines

The Gastrointestinal System Is Disturbed Nicotine also affects the stomach and digestive system, often causing these troublesome symptoms: Indigestion and heartburn Nausea and vomiting Diarrhea Peptic ulcers Dry mouth Similar to the negative effects on your hormones and brain, nicotine can cause you to feel physically ill

32 The strongest evidence for a role of individual carcinogens as causes of lung cancer is for the PAH and NNK, which reproducibly and robustly induce tumors of the lung in laboratory animals

However, inhaling vapor still carries some risk

The advertisement also referred to the interesting features of the Camel cigarette exhibit, including the dramatic visualization of nicotine absorption from cigarette smoke in the human respiratory tract and giant photo-murals of Camel laboratory research experiments. At a time when laboratory science had garnered especial admiration, the advertisement linked clinical medicine to the authority of investigative science.27 Along with directly soliciting physicians, the tobacco advertisements portrayed a glowing image of physicians in both medical journals and popular magazines