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Offspring Epigenetic Regulation A growing body of literature has demonstrated that environmental stimuli, including maternal substance use, can alter epigenetic regulation and impact gene transcription 138

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While the long-term health consequences of cannabis smoke are not yet well known, cannabis smoke contains carcinogens, respiratory irritants, and other harmful chemicals, said John Bellettiere, Ph.D., M.P.H., assistant professor in the Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego