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In vitro and in vivo evidence shows that cigarette smoke contains glycotoxins. These glycotoxins are highly reactive glycation products that can rapidly induce advanced glycation endproducts (AGE) formation outside the cells28, 29, 30

Another limitation is that smoking, whether measured individually or geographically, is often correlated with other cancer risk factors including air pollution, occupational exposures and dietary factors

While nicotine may stimulate specific biochemical pathways, cigarette smoke contains thousands of toxic chemicals that significantly raise the risk of cancer, cardiovascular disease, respiratory illness, and premature mortality

Living with another health condition, such as an autoimmune disease, could make you more likely to get dermatitis

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