cigarette smoke induces cytoplasmic p53 accumulation smoke-induced toxicity consequences of intracellular iron dysregulation and ferroptosis The Content – Science Education

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25 September 2017

In conclusion, this is the first study to offer direct evidence that smoking during pregnancy can exacerbate drug-induced liver injury in offspring mice later in life by modulating hepatic miRNAs

Similar to wtp53, post-transcriptional modifications such as phosphorylation, acetylation and ubiquitination can also regulate the level of mutp53

Therefore, shifting the balance between these signaling pathways can determine the outcome between cell death and survival in irradiated cells [15]