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What the research tells us There is modest evidence that pre-surgery behavioural treatments help people stop smoking, at least in the short term

Addiction: A term used to indicate the most severe, chronic stage of substance-use disorder, in which there is a substantial loss of self-control, as indicated by compulsive drug taking despite the desire to stop taking the drug
Transient down-regulation of neonatal rat brain mu-opioid receptors upon in utero exposure to buprenorphine

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