TSET Discovery Grants
US$ 23.63
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Description
New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma
Meng, Y (2022) SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism
Most importantly, an interesting crosstalk between p53 and its VDR transcriptional target is also highlighted in SC suppression, which opens the way to promising pharmacological strategies involving synergistic combinations between mutp53 reactivators and vitamin D
It uses tobacco sticks that contain nicotine, which is addictive
Episode 11
