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In 1965, among adolescents aged 12 to 17 years, 125.5 of every 1,000 smoked a cigarette for the first time

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N-methylputrescine then undergoes deamination into 4-methylaminobutanal by the N-methylputrescine oxidase (MPO) enzyme, 4-methylaminobutanal then spontaneously cyclize into N-methyl- 1 -pyrrollidium cation

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Statements Author contributions MB, SV, NK, and HL contributed to the literature review and writing of the manuscript