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Benowitz, Pharmacology of Nicotine: Addiction, Smoking-Induced Disease, and Therapeutics, 2009

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All of this baggage only complicates Ritsuko and Gendo's relationship, which becomes so tainted that it ultimately results in both of their deaths

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A smoker typically absorbs about 1 to 2 mg of nicotine per cigarette due to the process of inhalation and inefficiencies in absorption through the lungs