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[161] find that the activation of IB is critical in the phospho-acetylation of histone H3 on the pro-inflammatory gene promoters in response to CS stimuli and the histone H3 phospho-acetylation is critical for the activation of NF - B -directed gene expression

1973 IARC Monographs on the Carcinogenic Risk of Chemicals to Man

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Previously, using different cellular and animal disease models, colleagues have shown that blocking the expression and release of SASP factors could delay and prevent the initiation and progression of CVDs and cancers [11, 19, 20]

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