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Such miniature vessels from the Maya region, called flasks or poison bottles, are believed to have contained materials used in small amounts such as perfumes, medicines, spices, poisons or pigments (Loughmiller-Cardinal & Zagorevski Reference Loughmiller-Cardinal and Zagorevski2016) and are sometimes labelled as tobacco houses, suggesting that they contained tobacco snuffs (Houston et al

However, the same stimulating effects that improve focus in one person may worsen anxiety, insomnia, irritability, or overstimulation in another

Its pharmacologic and psychodynamic effects make stopping nicotine consumption very difficult, with potential withdrawal symptoms including cravings, anxiety, difficulty focusing, irritability and depression

However, findings from a comprehensive systematic review indicates that, when juxtaposed with probenecid, benzbromarone is associated with a reduced frequency of adverse effects

For the calculation of the diluted earnings per share, the weighted average number of shares reflects the potential dilutive effect of employee share schemes