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Inflammasome assembly leads to caspase 1-dependent release of proinflammatory cytokines IL-1 and IL-18 as well as to gasdermin D (GSDMD)-mediated pyroptotic cell death, facilitating the extracellular release of IL-1 and IL-18 45)
Nine in 10 cases of COPD are due to smoking cigarettes

Smith, Ed.D
