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Once in the brain, nicotine binds to receptors that release neurotransmitters, particularly dopaminea chemical that triggers feelings of pleasure and reward

On the other hand, heat-not-burn products heat tobacco to significantly lower temperatures that do not exceed 350 degrees Celsius, without burning it, and therefore produce no smoke

Physical and chemical characterization of smokeless tobacco products in India

Nicotine stimulates the cardiovascular system, leading to an increase in the standard resting heart rate for an individual of either gender, age, or fitness level

Chemicals in cigarette smoke also make it harder for our cells to repair DNA damage