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doi:10.1016/j.ogc.2014.02.001

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Similarly, Sleiman and colleagues (2016) found that when they increased the voltage applied to a single-coil device from 3.3 to 4.8 V, the mass of e-liquid consumed doubled from 3.7 to 7.5 mg/puff and the total aldehyde emission rates tripled from 53 to 165 g/puff, with acrolein rates growing by a factor of 10

These findings align with a prior study that reported an earlier TTFC had a significant direct effect on increased 4-(methylnitrosamino)-1-(3pyridyl)-1-butanol (NNAL) levels, but the relation was also not mediated by CPD 12

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