cigarette smoke induces cytoplasmic p53 accumulation Molecular Impact of Conventional and Electronic Cigarettes on Pulmonary Surfactant P53 and the Ultraviolet Radiation-Induced
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Lo W, Parkhurst M, Robbins PF, Tran E, Lu Y-C, Jia L, et al

Cai et al., 2009

doi: 10.3389/fonc.2022.919118

proposed a highly tumor specific TP53 delivery system based on CRISPR/Cas9 genome editing technology that can replace mutant TP53 in the tumor genome with a functional copy by homologous recombination, thus restoring normal p53 phenotype in tumor cells [174]

Protective role of glutathione
