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Description
It appears as brown to black patches on the lips, concentrated on the lower lip and vermilion border, caused by nicotine and tobacco chemicals stimulating the pigment-producing cells in the lip tissue

Kahn RS, Certain L, Whitaker RC: A reexamination of smoking before, during, and after pregnancy

Methods: This research examined a random selection of ten graphic novels chosen from the main library in a provincial Irish City

Alternative treatments include acupuncture, aversive treatment, and hypnosis

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