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An inherited condition called alpha-1 antitrypsin (AAT) deficiency enlarges the peril of early-onset emphysema, particularly among smokers, as highlighted in Yale Medicines Fact Sheets. Heart disease : As nicotine raises blood pressure and increases heart rate it contributes to a higher risk of heart attacks, stroke, and other cardiovascular problems

Given that young adulthood is a time of increased physical access to substances, understanding how cannabis interacts with mental health during this specific life stage is an urgent public health priority

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70,72 Mental health, beliefs about smoking, perception of schoolmates smoking, and other substance use are additional factors that can influence an adolescents risk for smoking and nicotine dependence

Their widespread popularity in the region stems from strong brand trust, extensive retail distribution, and stable nicotine consistency