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In a primary care setting, physicians can offer a brief counselling intervention using a five-step algorithm called the five As (ask, advise, assess, assist, arrange)

We excluded pregnant women, people who smoked only roll-your-own cigarettes, people concurrently enrolled in a smoking cessation trial, people who smoked fewer than 7 cigarettes per week, and people who at baseline reported living in the same household as another study participant
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Remarkably, nicotine causes dopamine release lasting more than an hour in the nucleus accumbens, which contributes to the lingering effects you may feel after smoking
doi: 10.1007/s198-002-8342-9
