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This is a Goodwin card issued in 1890

investigated the relationship between the adverse effects of EGCG treatment with dose and administration route by giving EGCG (108, 67.8, 21.1, and 6.6 mg/kg/d) orally or intraperitoneally to mice (230)

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Smoking Causes Dry Mouth Cigarettes reduce saliva flow, which normally helps wash away food particles and bacteria