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Biological causes: Tobacco use induces neurochemical changes through stimulation of nicotinic acetylcholine receptors, which prompt the release of neurotransmitters that produce pleasure and satisfaction, according to the third chapter of the book Neurobiology of Addictions published in 2016 by the Oxford University Press

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The paucity of evidence regarding their potential detrimental effects to both oral health and systemic health makes these questions difficult to answer