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PRODUCTION, SUPPLY AND VALUE CHAIN Supply Footprint, Trade and Value Capture Production by Country Manufacturing Footprint and Supply Hubs Capacity, Bottlenecks and Supply Risks Value Chain Logic and Margin Pools Route-to-Market and Distribution Structure 8
From a clinical point of view, the increased hepatic metabolism and the consequent reduction in plasma concentrations may lead to a decrease in the therapeutic effect of the drug, as evidenced in patients treated with olanzapine, where smokers showed a more modest reduction in psychiatric symptoms after 15 days of treatment [36]

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In August 2025, the Group repaid a 300 million bond at maturity

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