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Cardiac function in smokers and nonsmokers: the CARDIA Study

8 In a 2016 Cochrane Review citing evidence from two randomized controlled trials totaling 662 participants, those using nicotine-containing e-cigarettes were more likely to achieve six months of abstinence from conventional cigarettes compared with those assigned to non-nicotine-containing e-cigarettes (risk ratio 2.29, 95% CI 1.054.96)

It is also possible that tobacco-naive individuals who begin to use electronic cigarettes may have different metabolic parameters compared to former smokers who switch, as is suggested by our analysis of the pod-based users

Pressurized canisters typically have a positive pressure no greater than 3 pounds per square inch of pressure (psig) to reduce the likelihood of condensation inside the canister (USEPA 2022o)

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