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We thus here sketch a roadmap for application of multiscale in silico models, suggesting how the power of mathematical and computational modeling methods may augment and illuminate this significant public health problem

There are many treatment options for lung cancer

Although non fatal risks appear lower, especially for low TSNA Swedish snus compared to products used in Asia or the US, the association with fatal events underscores the potential danger of chronic oral nicotine exposure to the cardiovascular system (7, 18)
