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But "safer than smoking" is a low bar
It too has been associated with secondhand smoke
Moreover, immune checkpoints can regulate other biological process in tumors, such as self-renewal, epithelial-mesenchymal transition, metastasis, drug resistance, anti-apoptosis, angiogenesis, or metabolism (75)
Unfortunately, smoking can be a major one
The report noted that the shape and construction of e-cigarettes can make them more likely than other products with lithium-ion batteries to behave like "flaming rockets" when a battery fails
