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Whereas complete information on all the potential risks and benets of ENDS is not yet available, there is sufcient information to allow ACS to act now with a clear focus on the primary goal of ending deadly combustible tobacco use, which is responsible for approximately a one-half million deaths per year and 30% of all cancer deaths in the United States

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Report on the scientific basis of tobacco product regulation: Fifth report of a WHO study group

Smoking and Your Heart and Blood Vessels Smoking is a major risk factor for heart disease