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For non-prescription use, products with less than 0.3% delta-9 THC containing CBD, delta-8 THC, and other naturally occurring cannabinoids derived from hemp (cannabis containing less than 0.3% delta-9 THC) are legal and unregulated [14] at the federal level, but legality and enforcement varies by state

A dose-response trend was also present with increasing ORs observed for higher levels of smoking (1-9 cigarettes daily: OR = 1.05, 95% CI: 0.95, 1.17

Nonetheless, people who have mental conditions are at a greater risk of early death, up to 20 years earlier than the population at large, as reported by the Lancet Psychiatry Commission in July

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