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The prevalence of concurrent use of MF and/or RYO cigarettes and waterpipes slightly increased from 8.7% to 9.8% (13.6% considering only those who were current smokers at follow-up)

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43,44 In addition, a significant fraction of the carbonyls generated via sugar degradation dissolve into and are thus diluted by the water in the bowl, resulting in the corresponding dilution in the smoke

ACKNOWLEDGMENTS This work was supported by National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI) R01 HL139239, NIH/NHLBI R01 HL139369, NIH/National Institute of Environmental Health Sciences (NIEHS) T32 ES007324, NIH/NIEHS T32 ES007126, NIH/NIEHS P30 ES000260, and NIH/NIEHS P30 ES010126