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Quitting smoking gradually reduces the risk, although it does not return to the level of never-smokers

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This means it could displace other protein-bound drugs (examples include anticoagulants like warfarin, listed in the examples below) and cause unexpected side effects

[74] A 2016 review states that "The highly addictive nature of nicotine is responsible for its widespread use and difficulty with quitting." [7] Young adults and youth [edit] Addiction and dependence [edit] E-cigarettes use by children and adolescents may result in nicotine addiction

A 2018 study found that the top three preferred tobacco brands among 72.1% of current middle and high school student smokers were also the top three most advertised brands