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According to WHO and tobacco-control data, at least 34 countries have banned the sale of vapes outright

Middle East and Africa Cigarette Market Size and Forecast (by Value USD Million and Volume in Units) 9.1

However, after adjusting for confounders such as cigarette smoking, these associations were no longer significant, with an adjusted odds ratio (OR) for lung cancer of 0.62 [95% confidence interval, (CI): 0.32-1.2] among individuals with 60 joint-years of cannabis use, indicating no significant association (8)

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If the facts of a case implicate a potential misuse or modification defense, it is important to anticipate such an argument and be prepared to rebut it, including by the development of expert proof that any alleged misuse or modification did not cause or contribute to the incident