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The first RAPP tranche afforded the ability to explore new regions like Southeast Asia and the Caribbean, and the second tranche will provide lasting staying power, sustaining the initial efforts and making programming in these regions a core part of the EDP portfolio for years to come

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Chewing tobacco users have similar or even higher levels of nicotine than the smoker who uses a pack or more a day

Because DSM-5 combines dependence and abuse, studies addressed whether criteria for nicotine use disorder could be aligned with other substance use disorders (45, 71, 181), potentially also addressing the concerns about DSM-IV-defined nicotine dependence