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Khat: pharmacological and medical aspects and its social use in Yemen

The number of patients with COPD is nearly 299.4 million adults in worldwide [5,6,7,8]

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Indeed, while nicotine in normal doses is not as dangerous as perceived, the Surgeon Generals report in 2014, The Health Consequences of Smoking50 Years of Progress, surmised that nicotine has acute toxicity at high doses and activates biological pathways that upsurge the risk of disease

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