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This is basic toxicology 101, a foundational principle every first-year med student learns: The dose makes the poison. Paracelsus, the father of toxicology .[20] Just because something occurs naturally in trace amounts doesnt mean its safe or beneficial in highly concentrated, pharmaceutical-like doses

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American Cigar went on to acquire many competitors, and established corporations to acquired competing manufacturers, jobbers, and distributors in the USA, Cuba, and Porto Rico