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Description
SIRT5 prevents cigarette smoke extract-induced apoptosis in lung epithelial cells via deacetylation of FOXO3
Evaluation of lungs from patients with COPD finds the predominant histologic and molecular changes to occur within bronchial epithelial cells 2
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doi: 10.1038/s41598-020-63290-3 29 FilipponiDHobbsRMOttolenghiSRossiPJanniniEAPandolfiPPet al
This demonstrated that transcriptional induction of PUMA and NOXA accounts for all p53-induced apoptosis
