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There is ample evidence to support that habitual smoking is a primary risk factor for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD), immune-mediated inflammatory diseases, and a variety of cancer types [13, 9, 10]
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The rate has been gradually dropping for decades, due to cigarette taxes, tobacco product price hikes, smoking bans, public education campaigns and changes in the social acceptability of lighting up in public
Nicotine is the substance responsible for addiction to traditional cigarettes
