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Collectively, states have seen tax revenues fall by more than 10 percent in real terms since the start of the recession, the steepest and potentially longest lasting such drop in any of the last four economic downturns dating back to the early 1980s.[1] As a result, the fifty states, taken together, are projected to experience budget shortfalls totaling $113 billion in fiscal year (FY) 2012

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Although associations can be identified, temporal relationships or changes over time cannot be inferred

[84] Long-term nicotine use affects a broad range of genes associated with neurotransmission, signal transduction, and synaptic architecture

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