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10.1038/oncsis.2017.1 15

Decades of cigarette smoking research have shown that, in the short term, the number of acetylcholine receptors in the brain increases as the brain is continuously exposed to nicotine

Prince Albert cans were found almost everywhere in farming areas

E-cigarettes and related chronic airway inflammatory diseases E-cigarettes and COPD One of the primary mechanisms of COPD development is pulmonary immune-inflammatory response, with nicotine being the main factor contributing to this inflammatory response [55]

Existing public messaging on tobacco-free cigarette dangers rarely mentions this finding
