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A number of clinical studies examining toxicant exposure have demonstrated significantly reduced exposure to toxicants linked to cardiovascular disease, respiratory disease, and reproductive/developmental toxicity, in smokers who switch to using HTPs 30,31,32,33,34,35,36,37,38

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Document: British American Tobacco Zimbabwe Limited (BAT.zw) 2003 annual report

Return on Equity (ROE)

Since the most intercalating compound corresponded with the most potent topoisomerase I poison and cytotoxic agent, the 9-methyl ( 2 ) and 9-phenylpropyl ( 3 ) derivatives of harmine displayed a significant and broader spectrum of cytotoxic activities against the three tumor cell lines examined (human lung carcinoma 95-D, gastric carcinoma SGC7901 and hepatocellular carcinoma HepG2)