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This study indicates that nicotine could be beneficial for conditions mediated by chronic neuroinflammation such that delineating the neural mechanism mediating these effects could lead to targeted therapeutics for both neuroinflammation and cognitive symptoms in PLWH

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They were a part of a wide attempt by cigarette manufacturers at the time to circumvent the universal ban on cigarette advertising, which came about as both consumers and professionals became more aware of the harmful effects of cigarette smoking

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