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An in vivo study showed that mice treated with intracutaneous or topical tobacco smoke can have a decreased level of type I collagen

Any type of cancer We found one longitudinal observational study 17 , seven cross-sectional studies 14,16,19,21,23,24,38 , one case report 15 , and four cell/ in vitro and animal studies 18,26,27,31 examined the risk of any cancer

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We also considered nice-to-have features such as portability and remote operation