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UF Health News intern Kacey Finch contributed to this report.

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It can be addictive and using it has been shown to increase the risk of developing psychotic illnesses, particularly in adolescents

A multinational RCT of more than 8,000 smokers found no significant increase in rates of moderate-to-severe neuropsychiatric adverse events with either varenicline or bupropion relative to nicotine patch or placebo in those with or without psychiatric disorders (although the trial excluded patients with symptomatically unstable psychiatric conditions) [57]
